I don't know if a clone team would work. It's kind of a thin concept to base a whole team on. "You weren't the original bearer of your genetic material either? zomg d00d let's be friends!!!!11"
I would, however, love to see Joseph and maybe Ben Reilly again. I was never a huge fan of Nate Grey, mostly because I thought everything done with him could've been done with Cable without really losing much.
I think nate grey brings that kinda 'growing up in a sadistic future world' thing that bishop kinda used to.
plus he's younger and would mix with probably a different crowd.
The general theme for a clone based team would be them all feeling somewhat redundant or homesick because they have ultimately served the purpose of their own creation.
they are all made from bad people to twist the minds of the original heroes or fill out some other role, with perhaps some being better replicas than others, some being cybernetic replicas etc..
the common goal would be to find their place in this world, like ben reilly did with jessica jones, perhaps fill in superhero identity issues with the real versions of themselves and perhaps discover if their lives are just as much worth as their originals.
clones individually always kinda follow the same path, but we never really get to see them interacting together. Potentially, it could be very interesting.
I found Kaine, Ben Reilly, Joseph and Nate grey to be particularly interesting (especially nate when cable was still hinged power-wise). potentially she-hulk could go in here because her powers duplicate her cousins. Add a clor reconstruct and perhaps two more characters like agent x and multiple man and clor, you have this potentially limitless team with good interactions and the ability to go places.
they'd be like the ultimate reserves if **** hits the fan. The true last line of defense against evil.
all good stuff, don't ya think?