I expect reboots, rather than remakes, being the next big thing in Hollywood. It started with Batman Begins and some can argue that Rob Zombie's Halloween and the upcoming Friday the 13th (which many will probably consider a reboot since Jason wasn't really in the first film)
Ghost Rider, Blade, and Elektra are franchises I can see Fox letting go. I don't think they really need reboots or sequels.
Fox will probably look to reboot Daredevil in the style of The Incredible Hulk, though I hope they don't make the mistake of trying to imitate The Dark Knight. I loved TDK, but to give a cast and crew the direction of "do it like that" seems like the wrong move, most of the comic movies from Fox (I believe) suffered from far too much intervention from the studio.
Fantastic Four will either get another sequel in a few years with a new writer/director or will get a reboot. X-men may get a reboot, which is so-so. The X-men films weren't horrible but they failed to truly make it about the X-men and focused it on their literal poster boy Wolverine, so a reboot could serve it well.
I think Sam Raimi can succeed and make up for the last film. I think he and the rest of the cast/crew were under lots of pressure. They weren't sure they would be getting another film so they probably felt that number 3 was their last chance to deliver everything they still wanted to tackle and the film suffered.