The actress or the character? I haven't seen eps 2-3 yet.
In any event, just change it to a European business tycoon then. Don't see what her religion has to do with anything: she has armed mercenaries in her employ, and she's used death threats, so I think she's not above doing immoral things.
Re: the Vatican, interesting idea but I'd be surprised if that's the case. Admittedly, this show has a certain "heartland" quality about it, but these days the Vatican is a little too controversial for most people to accept as an altruistic organization. On the flip side, the very PG and middle-America orientation of the show makes a Da Vinci Code treatment of the Vatican also too controversial.