Plot:
1) Mr. Hardy / the Vulture gets hired as the new Daily Bugle editor.
2) His daughter is Felicia Hardy, who frequently hangs around the office, and develops a strong attraction to Daily Bugle top photographer Peter Parker.
3) After falling in love with Peter, she discovers his other identity as Spider-Man.
4) Spider-Man battles Vulture, Vulture dies somehow.
5) Felicia blames Peter for the death of her father (Harry anyone?) and becomes the Vulturess (Green Goblin II anyone?)
6) Spider-Man takes down the other gendered Vulture too, but he has an emotional connection to this villain, different than anyone before.
Dun, Dun, Dun!!!