I always thought Voyager should have, in a way, used Wrath of Khan as a blueprint for that show. An older, bored, restless Admiral taking Starfleet cadets on a training cruise when a message comes in from Starfleet command about the disappearence of a Maquis ship in the badlands, which would ironically be near the training mission course. With Voyager as the closest ship, they go to investigate and are swept into the Delta Quadrant along with the Maquis. And as it would turn out, the Admiral's much younger brother would be the commander of the Maquis crew. Things play out in similiar fashion from there, with the Maquis joining the Voyager crew, a crew of cadets mind you.
I think it would have been interesting to watch the interaction between a group of cadets, basically space children caught up in what it means to be a Starfleet officer, reading the prime directives ever night before bed in figurative fashion, and then the battle hardened Maquis, at first nothing but traitors in the eyes of our young cadets. And then the possible interplay between a respected, proud older brother who happens to be an Admiral and his younger, brash, in your face, ass kicking, traitor brother. Both men united in that they want to get there crew home.
And I would have had a romulan in the show. A undercover Tal Shiar agent that poised as a Vulcan member of the Maquis crew. No Tuvok.
And the main villians of the show would have been the ancestors of a large group of World War 3 baddies who fled punishment in non-warp capable sleeper ships, fell through an unstable wormhole and into the Delta Quadrant. Rescued by a technologically advanced and kind race(idk), they conquer that world and other worlds, building a true "Terran Empire".
Anyway......