The whole point is: if Pamela Isley will be in this universe, she would be the femme fatale with a perfect beautiness like in the comics? I wouldn't be so sure. Someone in this forum theorized an eco-terrorist version of Pamela. Considering it will a sort-of-a-realistic point on the character, she won't be dressed with plant of course. Plus, an obvious choice for the character could be wrong in the wrong hands. Who knows how Nicholson could have been in the Schumacher universe? Or think about Jim Carrey in the Burtonverse or Lee Jones in Nolan's. They could have been AMAZING in their roles. Considering all of this, and looking at the age of Pattinson and the kind of casting choices until now, my top choice for Pamela is Anya Taylor Joy. She's a terrific actress, beautiful but with something weird and horrorific in her charme. Plus, she's doing a good career with directors, movies and roles noir/horror/thriller movies.