I think realistically we're looking at another Winter Soldier situation. The first Captain America movie opened modestly, but TWS opened a lot higher on its opening weekend thanks not only to good early reviews, but increased popularity of the character after The Avengers. I see the same thing happening here after Ant-Man's further exposure in Civil War. The team-up movies always boost the solos (I know Civil War is technically a solo film, but it's unofficially Avengers 2.5). I'm guessing Ant-Man and the Wasp will open somewhere in the neighborhood of $90-$110 million. I can't see it beating Homecoming's OW take from last year.