I always saw Harley as a cautionary tale, showing how unhealthy relationships like that are. Her misguided love for The Joker is the reason she left a life of helping people and began hurting them instead.
Supervillains aren't supposed to be role models, inspirations or empowering. Just as superheroes are examples of how we should act, villains are examples of how we shouldn't. Harley Quinn is a monster, yes she has a tragic origin like a lot of villains but she kills people for fun and is not to be emulated.
To me, the only emancipation that would make sense would be her leaving the Joker and the Harley Quinn persona, returning to being Harleen Quinzel.
The Joker is her obsession like Two-Faces coin, take that away and she stops being a supervillain.
I see a story where Harley leaves the Joker as the last Harley Quinn story, the only reason she paints her skin and wears clown outfits is to try to please the Joker, without him that goes too and she returns to a normal life.