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The plot for Bond 22 takes a great deal from the short story Risico, where Bond is working with a man who could be a double agent to bust a drug smuggling ring in Greece (you might remember parts of this from the movie For Your Eyes Only).
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It is surmised that the double agent will be the unseen boyfriend of Vesper Lynd mentioned in Casino Royale. As Bond tries to get to the bottom of this terrorist ring, he, having been supposedly kidnapped, would have the best information. Mr White is just a cog in a chain, while the boyfriend, rumored to be played by Gael Garcia Bernal (still in negotiation) would be the leader of a terrorist cell planning on staging suicide bombings in Europe, including England.
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The title may wind up being Risico, but that and Death to Spies, while fitting the story, don't really suit the Bond lore. Risico being the more exotic sounding, and closer to this tradition. Just like a working title of Die Another Day was Beyond the Ice, then Beneath the Ice, expect more title rumors to come about before a final one is announced sometime in 2007.