It is, it's an imbalance in the brain. Most people don't even know they have it until someone close points it out and tells them to seek help, or worse, they try to hurt themself. This was the case of someone close to me, he had a series of troubling events take place in his life and it built up to the point where he was sick of feeling sad and wanted out, he tried to kill himself but was saved by a friend. He was counseled and was given meds, he is now a happy person with his life back on track.
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