To really bring new life to the Predator franchise, they need to go back to the roots. No, this doesn't mean turning it into a retro-80s action movie in a jungle. Rather, they need to find pick a contemporary popular movie genre, and use the predator mythos and imagery as a tool for subverting that genre. Which would be tricky, because the most obvious popular modern genre, the super hero, is also the most resistant to being subverted this way ( "alien hunter shows up" is not actually an outside context problem in any way for said genre ).