Well, this was one hell of a ride. SSM is becoming one of my most fravorite cartoons. It's just that damn good.
Yes, I did have some gripes (mostly with the end of the symbiote arc), but that show is so freaking sweet as a whole, that it's hard to believe it. It managed to get a lot of material covered in this Season 1 and it all felt very fast-paced and intriguing.
SSM has great character development (I'm excluding Eddie Brock/Venom here). The show did great deal of justice not only to the main character, but also to the supporning ones and even to the villains.
Story-wise, Season 1 was good, but big part of it were the introductions of Spidey rogues gallery. Not that these episodes were bad, mind you, but now it's time for more elaborated and pronoged storylines, not just "who-is-gonna-be-the-freak-next-week" ones. SSM already built most of the foundation, so now it has to go up. Of course, that doesn't mean that they should stop introducing new faces; I, for one, can't wait for the Hobgoblin in Season 3.
The animation was a bit strange at first, but it can look pretty good, especially in the action scenes, which, for the record, are excellent as well (think of "Group Therapy" most, but the other episodes were good too).
So, IMO, for now SSM is solidified as the best cartoon for Spidey, and probably the best "new" cartoon from the last years. I can't wait for Season 2.