I guess it depends on how into the lore you are. Bolivar Trask is linked to Sentinels, and is the most famous Trask. Gyrich tends to be your national security guy, but tends to be more antagonistic than Val Cooper. Kelly is your anti-mutant politician, and his portrayal has wavered, but generally some portrayed as "convincible". Graydon Creed is your straight up David Duke, your gutter trash racist. Friends of Humanity is your neo-nazis/klan of the 90s. OG comic Stryker tends to fill the same role, with the Purifiers taking a more religious approach. The Sapien League and the Leper Queen are more obscure, and not that different. Stephen Lang is also linked to Sentinels, but people seem to prefer Trask to Lang. Cameron Hodge big deal is the personal betrayal.
Honestly, I feel Stryker and the Purifiers are a better update for the modern day. I still love with how The Gifted portrayed the Purifiers as a modern day militia, with very visible sweatshirts. Because FoH needs red hats, and that will be a no go with Disney.