Lol not sure why this turned from Maestro to Wolvie vs. Spiderman, but most of these fights boil down to the fanboys, no offense since most of us are fanboys if we admit it or not.
Fact that that argument carries back and forth so well shows if nothing else that both have reasons they can beat the other. Spiderman can't hit harder than the hulk, Wolvie has taken the best hulk hits and gotten back up and was good to go so the whole Spidey knocking him out is very tough to swallow. Wolvie has trouble keeping up with Spidey's speed on paper, but in their actual fight Wolvie did well and Spidey complemented his speed. Read the Sabertooth vs. Ms. Marvel fight long before Sabers upgrade, Ms. Marvel well above even Spidey's current strength gave Sabertooth her best punches and he took them and laught them off, not only that but he was slugging it out with her not slashing her, then she slowly wears out and even coments he keeps coming for more and she's getting weaker. Now add an adamantium skeleton, and Wolvies been buffed up past a jobber lvl sabertooth I'd think, and pull down the strength lvl by a good what 35 tons? Spidey may have the speed but what's it matter if Wolverine heals from every hit before Spideys fist is back in postition to hit again.
What's more read one of if not the first Sabertooth vs. Wolverine fight, got the comic myself

. Where Sabertooth hits wolverine and breaks his fist, that's how it should go IMO. Spiderman with superstrength should not be able to throw a 1,000 punches against the hardest known metal and feel nothing, sometimes normal ppl break their fists hitting someones face, now put 15+ton strength against unbreakable metal....
Now there are reason's spidey can win too, fact is spidey and Wolvie are damn near even and that's why the arguments are so heated, plus the fact that wolverine wasn't always a top contender only more recently has given weaknesses in his defense on beating anyone, but he's different now than when he started. Spiderman did have wolvie's head on a tomb stone and just couldn't hit him hard enough to do anything but make Wolverine smile, now if Hulk can hit wolverine hard and far stronger than anything Spiderman's capable of and wolverine jump back up, that's saying something.
My opinion is no real clear winner will be seen, we'll always be given a draw so arguments and hype like this can continue. Fact is if Spiderman wins then it'll slightly hurt wolverine's hype, and if Wolverine wins...well chances are Spiderman would be dead. Wolverine can't win more fights than he does for the simple fact that razor sharp claws are his trade mark, he wins and that means his opponents in the emergency room or the morgue.
Personally I think both sides hype both characters too much. In all honesty Spiderman probably can't wound Wolverine too much, but he can control the fight. Longer the fight goes more spiderman wears down and Wolverine starts to take over. Wolverine was created to be a Hulk villain of sorts and is a brick slayer more or less, he's made to take hits far more than the best Spiderman shot can give. But I'm still not taking anything from SPidey, like I said he can control the fight and get more hits in, but that doesn't mean he can win. It comes down to it'd honestly, no fanboy exaggerations, take 100's if not 1,000's of hits from Spiderman to wear wolverine down and even then 2 mins later he'd be back to full, it'd take one good tag from Wolverine to take spiderman out, but could he land it? Last thing I'll say on it is it does come down to endurance IMO, Wolverine once battled with Omega Red for 60+ hours straight, no breaks and was weaker by a bit then than he is now. If he can keep swinging for 60 hours against someone like Omega Red non stop, I just can't see it being possible for Spiderman to wear him out. If Spiderman can't wear him out, and Wolverine has proven to take far more than what Spiderman can dish out and keep coming....I in all honesty just couldn't see spiderman taking it short of a plot device like a building dropping on Wolverine.
BTW yes I'll admit Wolverine's my favorite char, Spidey my second lol. Just remember tho this is comics, and much like pro-wrestling typically the most popular guy wins lol. What looks good on paper, their powers, what they've done in the past and so on mean nothing if the writer could care less. I've seen Wolverine take a Hulk lvl hit and stumble backwards, then get hit by a non superstrength character and get knocked on his back, same with many other characters. So really if they fought it'd matter less on what they can/can't do and more on who was getting the push, and with Wolverine on a movie high, and a new spiderman flick coming out, I just couldn't see Marvel letting them fight or lose to the other atm.