Some of the humor didn't work for me, but I laughed really hard during that part.The "Motherf***er!" when he gets shot through the arm.
Lawd.
Some of it does seem a bit too "try hard". But i guess that is Deadpool's way... trying to over compensate. Hopefully they get that through in the film though, that his wise cracks and irreverent attitude is a facade.
But yea... looks ****ing bananas. The action looks really inventive.

Definitely looks much better than X-Men Origin's: Wolverine version of Deadpool. I assume William Stryker won't be the person to create Deadpool in this movie the same way he did in X-Men Origin's: Wolverine?
In his interview on Conan tonight he said it was the same people who gave Wolverine his powers or something to that effect.

No, Ajax and Angel Dust are the ones who create DP in this incarnation, though Skrein did mention Weapon X during SDCC and Helman is reprising Stryker in Apocalypse, so I'm sure that was a newly added bit of exposition to provide some continuity with the post-DOFP world.