EXCLUSIVE: Tim Miller, who has done strong visual effects work on X-Men and other VFX-heavy films, is negotiating with 20th Century Fox to make his feature directing debut on X-Men Origins: Deadpool, the X-Men spinoff film expected to star Ryan Reynolds. Rhett Reese and Paul Wernick are writing the script and Lauren Shuler Donner is producing. In X-Men Origins: Wolverine, Reynolds made his first appearance as Deadpool, also known as Wade Wilson, a smart-mouthed mercenary with terminal cancer who undergoes military experiments in an attempt to replicate Wolverine's mutant healing factor. He comes away with the ability to heal quickly, but for the price of being indestructible he is rendered severely scarred. His acerbic attitude remains, though, earning him the nickname "The Merc with a Mouth." Reynolds will next be seen starring as another superhero, Green Lantern for Warner Bros.