Druig vs Loki:
Boiler plate, "Eternals is one movie, not the highest quality, everyone is short on feats". Etc.
IMO, Loki should take this. Druig is an extremely powerful telepath, yes. However, on one hand: he is never shown even trying to effect the other Eternals, even when it would make a lot of sense for him to do so. There are a bunch of ways to interpret this, but most of them end up at some form of "Druig's power is not nearly so unbeatable as he might wish", with defenses against it possible.
On the other hand, we *know* Loki has mental powers. He's never used them for broad area "Make everyone in range my slave", but he definitely has high end feats, probably the best being "A teamup effort with Sylvie hijacking the mind of the Alioth". He also has proven ability to shield himself from sensory powers, the most extreme being "Heimdall, who can see the entire frickin universe, can't see me if I don't want him to".
Net result? At absolute worst, Loki goes "raise all shields", puts all his power and effort into protecting himself from mental attack or detection, and then just. . . walks up to Druig and punches him. Because while I grant that Druig is certainly buffer than a normal human ( to put it mildly ), he has zero combat skill demonstrated. Loki doesn't need esoteric powers to beat him, he can just punch the dude, or stab him, or etc.