See, in the subject of kryptonite, I wish that they had went more towards the way the comics went. In the books, there was only one original piece of authentic kryptonite known to exist on earth. That's because most of Superman's enemies don't need kryptonite to be a threat to him, so the authors never felt the need to have more of the rock around.
The makers of Smallville have admitted to including the vast quantities of green k because they wanted Clark to have challenges, but that is the lazy way out and really shows off their lack of imagination. If they wanted challenges, maybe they should have taken a cue from the comics and just gone with good ol' fashioned chemical spills, genetic experiments, guy caught in a mysterious explosion, etc, without the involvement of kryptonite anywhere in their origin. Those methods of creating villains who can actually stand up to Superman without needing kryptonite have worked for decades in the comics. Why couldn't they work for Smallville? Because the show's writers are too lazy to come up with legitimate physical threats, that's why.
Kryptonite radiation causes cancer, not superpowers.
