No, TASM2 will make either a similar BO or less than the first one, and TASM3 is not going to make much more because of franchise fatigue, etc.
When it comes to big summer cinema:
I'm not so sure about 'Franchise Fatigue'. For me it usually means something looses it's initial wow factor and it then has to rely on things other than that to bring people in. The impact of the real dinos in JP, The impact of a man flying, the impact of dude swinging through the streets at 60mph.
That magic and drawing power can and does fade but that results films mostly lose their advantage, not actually turning away the audience. Even ASM2 is still going to do big numbers...
That being said, I think the best way around contending with that is to present something new or some new angle or a 'reboot' that does something new.
For example, Bond has been around longer than any franchise and it's arguably stronger than ever. 'Franchise Fatigue' be damned. Granted, around the 3rd Brosnan film, it was getting 'tired' but that's partly because it was literally the same old thing. Ignoring quality that is. Then when they rebooted with Craig, there was something new but then into QOS, things got complacent and tired again, but then Skyfall offered something new and different. And that's really my point, the franchise is like anything in hollywood, first you lose that wow factor but then you have to give the audience something to get curious or excited about again.
IronMan was hitting this around the second movie and the third movie without avengers would a been a very telling thing imo. But post avengers and it offered up a curious new exciting angle for people to want to be a part of. "What happens after new york"
Batman has been around for a while, but Nolan did things it wasn't doing in cinema for the past 30 years. And I suspect snyder's ideas to really take it into new ground.
Superman is tricky because that is one situation where (initial)change is seemingly fought. I'm sure the new luthor alone will help this. If anything has gotten tired and hurt the brand it's that old style luthor over and over.
Xmen got tired around the 3rd(ignoring quality) and again, it was doing the same old tired thing. I feel after XFC, they finally have something new to offer. Not so sure about singer and the wolverine show returning, makes sense for financial security but I personally would have enjoyed seeing Vaughn do the real DOFP story with those leads.
Thor 3 will be more loki to be sure, not sure where else they can go. Another earth based story, another space fantasy story. Either way it's more thor and jane. As long as MCU has avengers they will be able to re-reinvigorate their properties going forward.
The nature of cap, fixes itself imo. Hard to tread the same ground over a franchise. Especially with new directors.
Spiderman imo is doing and selling the same thing it's been for the past 12 or so years. Only with new actors. What it has to offer
cinema is the same. The cgi swinging and gobling gliders and catching the girlfriend...etc
Maybe this S6 thing will change all of that.