I suppose I'll throw my ideas into the mix.
"How would Dread do..."
Venom: Lethal Protector: This essentially a personal thing with me, since I was getting into comics strongly around this time, and Venom was a character I identified with during a rough patch of time in my childhood. But I always felt that this potential period, of Venom moving away from his hatred and revenge of Spider-Man and towards his more ambitious goal, protecting and avenging "the innocent" (after all, his own motive for attacking Spider-Man was that he felt Spider-Man took away his innocence, as well as the innocence of others around him) was mishandled almost from the start. Firstly, it was the 90's, and there were limits to what you could do in the line of "maturity". No Marvel Knights, no MAX comics, etc. We still had fads like hologram covers and so on. Secondly, too much of an effort was made to make Venom into a mainstream superhero, when he should have been an anti-hero like The Hulk or Punisher. Thirdly, there was too much conveluted crap involving the alien symbiote, which overshadowed Brock as a man, a feat that has endured almost throughout the character's history. Everyone thinks Brock is a weak character because he wasn't, oh, the father of Peter's best friend or something. He wasn't developped well, but all this wacky sci-fi crap with symbiotes was overdone. The point of Venom was that Brock was a man who did have his morals, but when his world collapsed all around him, he snapped and then was given power by another tragic being.
I always saw Venom as being in the gray area of Marvel. He's a vigilante but a monterous one, ripping criminals apart and still eating brains, marking his territory with blood to drive fear. Venom is the Id behind Brock. Brock as a man continues with this struggle, this mission to avenge and protect innocence, because he feels there is nothing else he can do. He is hunted, hated, feared, etc. He has to avenge the innocent because he is forever trying to salvage his own, which he cannot. Venom would be the savage Urban Legend type of monster that hunts the wicked, and Brock would be the man who lives in harmony with the monster inside him, forced to live a nomadic existence because of it. Also, I would stop the notion that the alien symbiote is always "evil". Why are aliens always evil? That's the easy way out. I saw the symbiote as simply being what it was; needed to feed on a host body to live and the by-products of that provided the host power, but also altered the mind. I saw Brock and the symbiote merging as one in a bond that is almost like love, but not love (the lonely Brock would even imagine the asexual symbiote as a female voice and such, but that is purely subjective). And of course, few have Venom's twisted, dark humor in battle. I figured in this role Venom could have been more interesting, and I even wrote a fan-fic about it.
Moon Knight: I've had ideas on revamping Moon Knight for ages, but unforunately the dilemma is; do you have someone else become Moon Knight, or stick with Marc Spectre, who could be interesting in his own right? I always saw Moon Knight as an occultish, pulp hero in the line of The Shadow and The Phantom. Unfortunately, Marvel is a superhero company and so he came off eventually as a poor man's Batman, which is never going to work. I would kept the origin the same but expanded on the occult elements. For example, Spectre became Moon Knight when the Egyptian God of the Moon, Knoshnu, revived him from the dead after he was left in the desert to die by his fellow merc, Bushman. That's fine, but let's add some more. Take a page from The Phantom and claim that Moon Knight has existed almost from the rise of the Egyptian empire, the essence of the Fist of Knoshnu moving from one host to the other, passed on to someone new when the next one dies, to give the impression that Moon Knight, like justice, is immortal, and never dies. Marvel could use a "ghost who walks" in a sea of superheroes and mutants.
And for the powers. Moon Knight I always saw as brilliant because his very powers allow for his power levels to rise and fall, therefore, you can have him potent in one story and weaker in another for drama and it's all accurate! Have his strength rise in proportion to the phases of the moon; say, a full 3 ton class on a full moon, no gains during a New Moon, and various levels of strength in-between (Crescent Moon, Half Moon, 3-Quarter Moon). I would also allow the transformation into Moon Knight to be more mystical. The costume is a mystical one that forms over him at night, and he is forced to his task of fighting evil and righting injustice, otherwise his body will deteriorate. Moon Knight would also be able to travel where-ever moon light travels, responding and appearing almost automatically to moments of distress or evil. And, to get him out of overcluttered New York, Moon Knight operates around Africa/Middle East/areas around Egypt or that sector of the world, where Moon Knight is such a strong superstition that children have a rhyme about him to say as a prayer at night. Because, of course, there has always been a Moon Knight. Some Egyptian themed weapons wouldn't be bad, but less of a reliance on Bat-esque armor or technology and more on his mystical powers of strength and teleportation (and of course, Spectre's own honed skilled, kept to their peak vigor when in the magical costume and guise of Moon Knight).
Moon Knight should also encounter not only human evils and immorality, but supernatural ones, too. And I'd see him as distant toward superheroes. I mean, how do you invite The Shadow to the Avengers?
As for Spectre's sanity...being a vehicle for an almighty hand of vengence can surely drive a man mad. Ever read DC's The Spectre? Moon Knight is made to react almost automatically to distress, just as the generations change, so must the host and identity of Moon Knight. A legacy, which Marvel has little of aside for Green Goblins (notice how they are trying to backtrack and do that with Black Panther). Does Marc see himself as just a tool of the god or a man worthy of such power under his own right? Instant tension.
That's all so far.