So wait, the PoE that Desmond has now - is that one a fake? Altair says "tell them I sent it away - to Cyprus" and then Ezio takes that PoE from Rodrigo which the Templars recovered from Cyprus. Then Ezio locks it away in the Coliseum for Desmond to recover - but then why is it that Altair is buried with his PoE? Anyone else think that the one the Assassin's currently own is a fake?
I'm assuming when they get it, Desmond will also retrieve some of Ezio's equipment that he left behind for him.
EDIT:
Just found this
Here is what I know, most of this I read from the Assassins's Creed Wiki.
There are many Pieces of Eden that have been created, and according to the wiki, the locations of 50 have been given, as shown on the map shown to Altair after Al Mualim's death.
Six Apples of Eden are known. The one Altair uses is the second Apple, and after the events of ACR it finds itself in the hands of Queen Elizabeth 1 of England and Mahatma Gandhi, until it was obtained by the Templars and destroyed in an accident while conducting experiments under Denver International Airport; they were trying to use it with a satellite so that they could use its power to alter the minds of the globe.
The one Ezio obtains is described as the sixth Apple, although it was never given a number. In 1506, Ezio hid it in the Colosseum Vault, and is later discovered by Desmond at the end of ACB. This is the Apple we see in the van at the end of ACR.
At the end of ACR we see a city of Those Who Came Before/First Civilisation being destroyed by some kind of solar flare. This is the disaster that has been predicted to occur once again in 2012. The location that the Assassin team arrives at is New York City, where the coordinates seen at the end of the ACB Da Vinci DLC point too, this also looks like the place Jupiter directed Desmond to as being a Vault for all the information collected from the different solutions the First Civilisation came up with to stop the disaster. Looking at the cutscenes at the end of ACR, it is possible the city we see being destroyed was located where New York City is located now.