In today's market? If Joe Q did what he usually does, which is give it almost nothing besides your "online teaser" that all books get, it would sink like a stone. Marketted properly like ANNIHILATION? Who knows. Marvel hasn't tapped their cosmic market for many years, though, and it may not be sustainable beyond "events". I would recommend big name talent, though. The sort of "far out" writers well known for doing well with space stuff. Gaiman and Morrison come to mind. Maybe start begging Alan Moore. Writers sell comics a lot of times, so if they got a hot writer (and artist), you could have a 17 issue series starring The Watcher and Ego and it would sell in the Top 25.