Darla is born in the late 16th century in the British Isles. Her birth name has never been revealed in either series, and Darla herself eventually forgets it. As a young prostitute, she emigrates to the Virginia Colony in North America and becomes independently wealthy but also contracts a fatal case of syphilis.[8] By 1609, Darla lies dying in the luxurious house she owns. She scoffs at a "priest" who comes to her deathbed before he reveals his true identity: the Master, leader of the elite cult of vampires known as the Order of Aurelius.[8] Darla despises the clergy and religion, a trait that would follow her as a vampire. The Master turns her into a vampire and renames her "Darla," meaning "dear one" in early modern English ("darling").
She spends four centuries torturing innocent people, often accompanied by Angel (until his soul is restored), before showing up in Sunnydale.[8] Darla's first appearance is in "Welcome to the Hellmouth", the first episode of Buffy the Vampire Slayer, aired in 1997. She breaks into Sunnydale High School with a student who goes there. Darla first toys with the youth, then her face morphs into that of a vampire, and she bites the boy.[9] Darla later appears in the episode "The Harvest", where she participates in the ascension of the Master, a very old and powerful vampire.[10] Darla's role in the series is more prominent in the episode "Angel", where it is revealed that she was Angel's sire and former lover.[4] Darla bites an unsuspecting Joyce Summers (Buffy's mother), making it look as if Angel did it. Angel eventually kills her.[4] She later appears in numerous flashbacks, illuminating her involvement not only with Angel, but also with Spike.[11][12]