His opponent's skill and and strategy is still going to be very important. There are some fights Trump will pick that you can lean into a bit, but others you need to avoid, because they feed into his base's most fervent "stick it to 'em" mindset and allow him to control the narrative.
Healthcare should be the sticking point, but there's a way to navigate the patriotism side and come out well against Trump, and I honestly think there should be some attacking there, or at least some awareness of how to counter Trump's inevitable attacks there with something energetic and genuine. I don't believe that attacking the Neo-Nazis would be a bad idea, and I'd have some analytics run into whether or not attacking the lies and deceptions of the Lost Cause would be a viable tactic.
I mean, I feel there is a way to appeal to people on the basis of "the leaders of the Confederacy sacrificed hundreds of thousands of good honest men, men who went out for loyalty to their local leaders, respect and love towards their fathers and brothers, and out of a misguided believe they were doing something right. But their leaders spent that blood and sweat out of cowardice about the future, out of selfishness for their wealth, and out of a treasonous hatred of their country. Brave men died so traitors could hold onto their profane economy for a little longer. Men were sent off to kill their fellow Americans for the sake of slavery, to die underneath a flag that today represents the worst aspects of their culture, the sins and perversions that slavery enabled. The red on the American flag? That comes from patriots dying to protect out freedoms. The red on the Confederate flag? Whatever brave men's blood may have been there originally is now drowned out and cursed by that of thousands of dead Americans, slain by terrists who hid their faces and brought shame to those who died at Shiloh, Antietam, or Gettysburg. It is a great tragedy that so many men were slain for such a vile thing as slavery. But it's a damn good thing the Confederacy lost. Those men buried in the ground? They're Americans. And we should remember that."