Blackheart definitely did not have any guilty feelings.

I don't think that's how it works.
Okay so Ghost Rider's penance stare can work on these guys. They're still much, much, much faster unless GR gets on that hell cycle chasing them around going "LOOK INTO MY EYES! COME OOOON! DO IT! I PROMISE NOTHING WILL HAPPEN!" because something tells me that that chain will not work on Hulk and Silver Surfer (they'd probably just pull him and send him flying or something.
GR has at least Hulk level strength but I don't think he has the weight to back it up).
So Surfer and Hulk take that and we've all established that Pheonix isn't getting too far fighting these guys that all have healing factors on insane levels. So it's down to Hulk and Silver Surfer for now. Surfer can probably just do the same thing with him that he did to Johnny Storm. Fly that sucker into the stratosphere and let him suffocate. If not then demolecularize him. Clearly Surfer can do this on a much larger scale than Pheonix (what he did to Galactus) so I think if he concentrates that all on the Hulk, the guy's screwed.
But hey, November Rain's right about Mephisto. No-one's touching that guy. He warps reality to suit his needs. Galactus probably fears him.