I have my doubts on Spidey, but I haven't seen the trailer yet. It just, from the sound of it, looks to be a very cluttered film IMO. Plus, I'm still iffy on Topher as Venom.
I'm most looking forward to the Batman Begins sequel. The rumors we've been hearing so far all pointo to high quality, and unless Indiana Jones 4 is completed in time, I think the film has a good chance of being the biggest hit of summer 2008.