Ok, I think I've mixed myself up somewhere.
So with DAT FASS supposedly playing Desmond (And his ancestors) who would we cast as his ancestors?
Altair - Vin Diesel? Has the middle Eastern appearance and played a similar character in Riddick
Ezio - Eric Bana. He doesn't get to play charming humourous guys very often but he's a top actor.
Edward - Chris Hemsworth. They look alike physically and Chris Hemsworth as a pirate FTW.
Haytham - Guy Pearce. He could easily play kind of an aristocratic evil James Bond.
Connor - No idea here.