There are only two truly detrimental things that can be directly blamed on Joe Q.
1)Sins Past: Joe Q edited the story(JMS's original script called for the kids to be Peter's).
2)OMD/BND: Joe Q edited the story (JMS refused to write the story, but was contractually obligated. In the end he was only partially credited rather than fully credited.
I would have put Civil War (again Joe Q edited the original script. Originally the Initiative lost) on the list, but Civil War led to World War Hulk and Secret Invasion. Both of which have turned out pretty damn good (in the case of Secret Invasion, it is more like so far, so good). It seems that anytime a decision is made in a Marvel book that the readers don't like, they instantly blame it on Joe Q.
Yes Joe Q has made some serious errors, mostly revolving around Spidey, but the entire mans tenure can't be blamed for things you don't like about Marvel. Writers still write, so at least pass the blame along to where it belongs. And generally speaking, each book has its own editor, so to a degree, Joe Q isn't in charge of every single decision, for better or for worse. It is purely immature, unrealistic and petty to blame Joe Q for everything. Blame him when it is factual, not when it is convinent.