Hell, I'll take a stab at this. Tony Stark is sitting at a meeting half-listening while he tinkers with the next generation Iron Man helmet (think a hybrid between Bleeding Edge and All New! All Different!) when it's brought up by Pepper or Happy or whomever is in charge of Stark Enterprises hammers home the point that their stock has been dropping for the last three months due to Tony being distracted with his Avenging in general and the Civil War in particular. Furthermore, they've been losing marketshare to a company called "The Future Foundation", led by an Elon Musk-esque Reed Richards. Reed is an electronics and technological genius while his childhood friend Ben Grimm is the mechanical hands-on type as well as the one who keeps Reed grounded in reality.
The Future Foundation's primary source of buzz has been the latest generation of all-electric Fantasticars, a prototype vehicle that harnesses and improves upon the repulsorlift technology that Howard Stark and his son both worked on and adds in things like self-drive and improved AI that helps the owner be more productive in general. In secret, Reed and Ben have been working on their one dream project - private space travel. Reed can get the electronics to work, Ben can design the ship with the aerodynamics and engines and design the nuts and bolts down to the last clip, but they need someone who is an expert in astrophysics and space telemetry to help them put the finishing touches on the project - Reed's estranged former college roommate, Victor von Doom.
After come cajoling and begging, Victor signs on to the project and the relationship appears to begin to thaw and he and Reed start to get closer. Ben still doesn't fully trust Victor, however.
Finally, with Victor's help they break down the final obstacles of (insert science problem here) and have a planned test flight involving Reed, flight engineer Ben Grimm, pilot Johnny Storm, and his sister evolutionary biologist Dr. Susan Storm. They take off, yada, yada, yada cosmic rays and when they come back it's revealed that Von Doom (who had been working as an ersatz mission control) had sabotaged the flight because he was still jealous of Reed from their college days and wanted to "win" once and for all, even if it meant killing the other three alongside Reed. Victor takes off to his homeland of Latveria in order to take advantage of their non-extradition policy with the US.
Continue the story from the early issues of the comics with the underground monsters leading to a confrontation with Mole Man. With the Mole Man finally defeated, and the public cheering, the Four see on the news a story about a coup taking place in Latveria, with Victor Von Doom taking over the country, putting on the ceremonial armor and renaming Latveria Castle Doomstadt.