One of the things I've said for years on these boards is that I personally don't think that Dr Connors should transform back and forth from the Lizard several times in the movie.
A fast transformation is fine in the comics, but the idea of a man transforming so quickly into a giant lizard, and then doing it again several times, isn't very-- dare I say it -- realistic in a screen version.
I've always hoped that Connors' transformation into the Lizard would be a slow one, like Jeff Goldblum in
The Fly. Thus we can see the actor going through various stages of practical makeup before the full CGI Lizard comes in. Also, the transformation should just happen once, with Connors remaining the Lizard until he's cured, imprisoned or dies, whichever happens in the movie.
PS - I don't want him to die.