I was reading an article with a theory I never considered: if they get the gauntlet off Thanos, will a sacrifice be required to wield it? Thanos obtained the Soul Stone already, but does that mean the stone is fair game for anyone to use now, or does every person using it need to make that same sacrifice Thanos did? If it does, then that means whoever ends up with it has to kill one of their own.
If this comes to pass, sadly I think that would spell doom for Cap. He'd be the first to line up and be the sacrifice. Plus, he did make a remark about "We don't trade lives" in IW. But, what if victory requires exactly that? I think this theory may have some legs.