If they do acknowledge it, then they're really stuck when it comes to explaining how the disintegrated people come back to life. Do they not explain it for a year?
Of course, it depends on what the acknowledgement is. Maybe it's just that the confederacy aliens are bracing themselves for an attack by Thanos. But they don't show any of the disintegration at all. In which case, why does none of that happen?
And if people do disintegrate, but Daisy cracks apart the planet, then there's no chance of beating Thanos unless the AOS change the timeline.
But what if the timeline that the AOS want (where the planet doesn't crack apart) is not the timeline/scenario that Dr Strange wants where they are able to beat Thanos? Then they're all doomed either way.
At this point, the ending of Infinity War made it difficult for any Marvel TV show to be set after May 2018 and before May 2019. So they can't acknowledge any dates in these shows.
Does that mean that it's still either 2017 or early 2018 in all shows going forward (eg Cloak and Dagger, Luke Cage season 2, DD season 3 etc)?
And what about AOS season 6? That's really the difficult one, unless of course they are cancelled (which would probably be the best solution as far as reconciling the storylines go).