Doctor Octopus Vs Gorgeous George
Okay, the X-Mansion will have very little to help here with either character, as neither have ever been there. By George's last appearance he wouldn't even know what the X-Mansion was (being that his last appearance was back in '94)... just that it was a basic mansion. Doc Ock, however, is more modern and if he's like anyone in the world, he will know about M-Day and about how the Mansion has been opened for mutants and such. These days, Xavier's is fairly well known. Thus, while he has never been to the mansion, and would know nothing of it... he will at least have the knowledge that the X-Men are housed there, that their is something more to the mansion than just it being a mansion.... and as always, when it comes to Doc Ock... knowledge is power! That said, I figure Doc won't know George either, but one look at the guy can show that he doesn't have a normal physic. Now granted, he won't know what is differant, but he'll at least know to be cautious. And I'm going to assume that George would know Ock, as Ock is fairly high profile. Though George is from Australia... so he may not know. Either way, Ock isn't hard to figure out.
Doc is smart and he may be able to find a way to play with the mansion and find it's security systems... or break down into the elevator shaft and find the basements and find other things to use against George, but really that's up in the air. I'm sure he can find some way to use something to his advantage, and he has the intelligence to make that assumption with, but I think in the end end it'll come down to a "fist" fight. So let's play that out.
George is very malable, can change his shape and ooze into a puddle and such. The thing is (and correct me if I'm wrong) but I don't recall him actually expanding himself to great lengths, or throwing parts of himself... so while he is very malable, he's still going to have to get in there to fight... or at least within range of Doc's arms. Now if Spidey isn't fast enough to dodge Doc's arms (he does sometimes, but most times he gets caught, even with his spidey sense) then George isn't going to have a chance. The arms couldnt' hold him, and they'd probably just cut right through him instead of hitting him... but remember, there's 4 majorly fast arms at great lengths distance from Ock's body, and they are all gunning for George. I honestly don't see how George can get close enough to hurt Ock! He'd but cut into a million gooy pieces before he even gets there. Even if he was able to throw stuff or expand and recover after each hit... Ock can use one or two arms to block or redirect anything that is thrown at him, while assaulting with the other legs. Offensive and Defensive at one time. Not to mention that they are in a school with a LOT of furniture and such. Not only is George dodging and defending against the arms themselves, but while two arms are tearing into George, another arm is lifting and smashing him with a school desk and the other arm is finding a nice television to smash over his head. Or maybe he's beating George with two tenticals while using the other two tenticals to smash the floor about George, dropping him through the floor. Or push come to shove he can just colapse the room or building onto George whiel protecting himself with his arms or using their great lengths to get himself out of a window.... if you want to get extreme about it.
George isn't just facing a man with metal arms.... he's facing four majorly quick foes with the a cunning genious guiding them from a safe distance. I like George... but Ock's got the experience, the reach, the speed, and the intelligence to knock George aside like an annoying gnat.
Winner - Doctor Octopus