My Doc Ock Top Five:
1. Revenge of the Sinister Six: Yeah, it's overblown and bloated with too many heroes at the end, but it starts out awesome and was entertaining throughout. Ock with adamantium tentacles unleashed! Larsen went out of his way to upgrade Otto into a 'Doctor Doom level threat' long before the lame ASM #600. And, as an added bonus, Wolverine isn't among the guest stars.
2. Web of Death. It would've been even better had Ock not died at the end and Marvel allowed new writers to build on the new emotional layer to the Spider Man/Doc Ock feud.
3. The Owl/Octopus War: This arc really showed just how vicious and nasty Ock can be. You know a guy is badass when he can scare the Kingpin enough to make him leave New York. And I love the fact that Ock was fully prepared to nuke NYC just to prove how dangerous he is.
4. Negative Exposure: This one shows how manipulative and cunning Ock can be, but I'm really tired of the 'knock-Ock-out-with-a-punch-to-the-jaw' routine.
5. Amazing Spider Man Annual #15: Doctor Octopus humiliates the Punisher, nuff said.