The central idea for the idea I had was Otto in a desperate search for a cure. He attacks Captain America and Wolverine and obtains samples of their blood. Finding nothing useful in the Super Soldier serum or Wolverines' DNA, Otto prepares for death. Then he makes an astounding discovery, there is one thing that can cure him: the strength enhancing formula developed by Mendel Stromm that turned Norman Osborn into the Green Goblin. Otto obtains the formula and studies it. He learns that with the formula, dose is the key. Otto uses the formula at a lower dose than what Osborn used, and it works. Otto is still left emaciated, but the radiation has been purged from his system and the healing factor in the Goblin formula is slowly restoring his body to normal, Otto goes into hiding just as Osborn finds out about what happened, thus setting up an eventual Octopus/Goblin War