As much of a Spider-Man as I am and as much as I liked TASM, I am going to have to go with MOS on this one.
Both have issues I have with them but overall, MOS falls in the "great" category for me while TASM falls more in the "good" category for me. However, I also think that future sequels to TASM have far more potential than future sequels to MOS (at least so far). One thing that hurts TASM a bit but benefits its sequels is the fact that TASM was more of a setup film. MOS was also a setup film but not to the same extent.
Both have issues I have with them but overall, MOS falls in the "great" category for me while TASM falls more in the "good" category for me. However, I also think that future sequels to TASM have far more potential than future sequels to MOS (at least so far). One thing that hurts TASM a bit but benefits its sequels is the fact that TASM was more of a setup film. MOS was also a setup film but not to the same extent.