Sounds good to me. Now that it's a two-film deal, they'll be able to take on more villains at a time and it won't matter because, hey, there's another film they can take the story too!
I say Raimi comes back as a Producer, they recast the main stars... then go with villains such as Lizard, Kraven, and maybe even Carnage making an appearance (done to make up for Venom's short appearance).
But focus MAINLY on Lizard and Kraven! I dunno... Black Cat and Mysterio would both be nice...
Who knows... I'd say only stick with 2 villains, but they've got two movies... why not 4? :P
I just had a thought... what if Sony's planning on a two-movie Sinister Six plot? That might not work out as well... villain teamups in films hardly ever work... I really hope they don't do this... but now that I think of it, it makes sense that SONY would think of Sinister Six as the "only possible route" for a two-film bonanza... now that I think of that, I don't know if this IS good news... :|