There weren't any "blond chicks" in the original episode, but there was a woman on the Enterprise crew who fell in love with Khan and helped him sabatoge the Enterprise. At the end, she agreed to be marooned with Khan and the others, where she became his wife. When Khan is found in Wrath of Khan, it's revealed that she died. I believe they had a son as well.
The blond woman in Wrath of Khan was a scientist named Carol Marcus, who had a history with Kirk (they had a son together, David, who didn't know that he was Kirk's son until the events of Wrath of Khan). The same character is introduced in the new film.