Could have been a great story but on the whole it was poorly executed, was too long, and many plot threads were largely unresolved. Now, I don't mind unresolved plot threads (the central conceit of writing a comic being that a new writer can pick and choose from unresolved threads to write a compelling and rich story) but for this story, which was blatantly marketed as being 'self contained' it's clear that there was no real resolution planned.
'The Other' in the cocoon at the end? Unresolved.
The affliction being the result of a curse? Unresolved.
Heightened Spidey sense? Under-utilised (and IMO unresolved)
I'm sure there's more. And, in response to JQ's standard response of 'Wait and see' , i'm afraid there's only so many times that excuse works before it becomes a pure cop-out.