Well, maybe Peter finally is going away for a long, long time...
http://www.comicbookresources.com/?page=article&id=42575
" Life goes on. Peter Parker fans will sort of fade away over the months and years, and you'll have a bunch of people who only know the new cast."
"This has been in the works for a few years now, and
the plan always was to make this the last issue and make it a definitive end for the character. It's been 50 years,a helluva good run. The 700th issue happening around the same time was just sort of serendipitous.
This type of thing has been done in comics before during the Silver Age when Julie Schwartz, Gardner Fox, John Broome and the guys at DC brought out new versions of classic characters like the Flash and Green Lantern. That's the kind of worldbuilding scenario we're playing with."