World The Fly and Spider-Man

I recently watched "The Fly" (1986) and realized that it could in a sense be considered a real-life, hyper-realistic interpretation of Spider-Man.

Seth Brundle becomes assimilated with the DNA of an insect throught scientific experimention, much as Peter Parker did. He then aquires increased agility and strength.

The difference is, much as would happen in real life, the combination of two very different types of organisms ins't going to result in some kind of flawless combination with superhero powers.

So, can The Fly be considered an unintentional realistic interpretation of the Spider-Man story?