I think other story avenues need to be considered other than she's the first person he saves. New franchise, new beginnings, new opportunities. A Lois-less film isn't gonna stop me from watching it.
Well i'm not saying that it would stop you, however there are A LOT of fans out there who may rethink about wanting to see this film if Lois isn't in it, because she is a CORE character to the overall mythologies.
Lois isn't simply a LI for Superman; and a lot of ppl understand that. Even though Nolan revitalized the batman franchise, he still stayed true to the core aspects of Batman's mythology:
1. Parents gets killed in a mugging
2. Bruce travels the world and learns how to become Batman
3. Bruce returns to Gotham as Batman and forms a partnership with Gordon
4. Bat Signal is created
The same thing is for Superman, he has a certain amount of things THAT NEEDS to happen in a film, to have them gone, would be harming the film like Burton almost did with his stunt, and Lois meeting Superman in his early debut, whether rescued or not IS A PART OF THAT..and there are countless of comic books that would back me up on this.
Out of ALL OF THE CHARACTERS that have been introduced in the mythology, Lois Lane has been there as long as Superman has.
Lois has been there longer than the Kents, longer than Lex, longer than Clark's ability to fly as well.
To take Lois away from Superman's early days would be more dumber than what they did with Batman & Robin the film.