Scarlet Spider Vs Sinister
I was debating on this match because at first I felt that Ben doesn't have much of a chance due to Sinister's vast array of powers and his experience and all that. But then I thought and decided to examine Sinister's powers and all I could regarding bios (as I'm kinda light on comic appearances).
So here's the deal.... Sinister is a huge threat... when he knows what he's up against. When he shows up on his own accord and is ready to play out a plan he's laid out... he's a huge threat, but someone comes along that he isn't familiar with, he'll defend himself to an extent... and then cut and run. He held up strong against the X-Men during Inferno, and X-Force/X-Man during Onslaught, while on his terms and knowing and preparing for the battle and setting the stage how he wants it. Yet, when Domina from the Neo, a much lesser threat, came chasing him down, and he didn't know her at all mind you, he cut and run... and not once, but multiple times. I want to say 13 times, but I could be off there. Sinister is a brilliant mind, and while he can fight, he's not best suited fighting. He's a major mental threat... not so much a physical threat. He had others due that work for him. And here he is against Scarlet Spider... someone who Sinister knows nothing about. He may be able to look up some old files on him, but he always plays with a person's mind by praying on their weaknesses... or he messes with them genetically... none of which he can do with Ben. And I feel that THAT greatly takes away from Sinister's ability to win this match. Also, Ben wont' know the X-Mansion... but neither will Sinister. He's been to the old one, but not since it's been rebuilt. All of it was destroied before... now it's all new, and Sinister will know nothing of it. Both are in the dark.
Now, with that, let's look at it a little more detailed. Let's break Sinister down:
Going by Wiki, some of my biggest fears against Sinister seems to be not as big a deal as I thought. I know he's shown telepathy before, but I can only remember minor things. Wiki confirms it in that he's only done things like keeping others out of his mind, and by controling others after touching them (and note, this isn't a huge thing with Sinister, as I don't really remember him even doing it, so it's not normal for him to do it, so it's not an automatic deal that he'll pull it out. Let alone someone with Ben's agility allowing himself to be touched). None the less, Ben is in no harm of telepathic invasion, as Sinisters telepathy is very limited.
Next was his telekinesis and such, but really it's nothing Ben's not faced before (whether through him or through Spidey's memories prior to his creation). He's used to force blasts (the main use of his telekinesis) as he dodges them all the time and is rarely ever hit by them. He's also able to move small objects... but the blasts and this are all easily noted, predicted, and prevented by the good ol' fashioned Spidey Sense!
And really the only other power that Sinister has is actual form. He can shapechange... but he can't fool Ben, as he doesn't know Ben nor anyone he can change into that would effect Ben. If he tried to turn into anyone Ben wouldn't know, he'd know instantly that something was up thanks to his Spidey Sense. Sinister knows nothing of Ben or Peter's spidey sense, so he won't be able to defend against it.
His malable body is really more defensive than anything and it won't take Ben out in any way. Then there's Sinister's fighting abilities. He can definately hold his own, but I am hard pressed to say he'd be a better combatant than Ben, and when it comes down to it, it'll be a fist fight. He is quick, but not as quick as Ben. He's strong, but I doubt as strong as Ben (though that one can be debated). He's smart... yeah, probably smarter than Ben, but let's remember... these Parker boys are extremely intelligent themselves... well ahead of the rest. He may not be Sinister level, but Ben holds his own. However, the mass majority of Sinister's intelligence is his genetics and manipulations, and none of which really applies in this match.
So in the fist fight, I think Ben's got it. Sinister will hold his own for a while, but Ben will be able to rely on his Spidey Sense to dodge physical assaults and any mental manipulation that Sinister may try. I feel that if he goes the same route as his first Venom fight and impact webbing Sinister, then stinger him, it will probably take him out, or at least slow him down enough for a severe beating that will finally render him unconscious. Even if that doesn't work, Ben's a smart and resourcful man. I trully think he can pull it off. It'll be a heck of a fight for him... one of those where you see his mouth through the bottom of his mask... but in the end... Scarlet Spider will be the one left standing.