I'm curious where you go with Real. How much of a role does she play. Thorne would be a good antagonist for her at least. Just because Falcone is gone and Real is mayor doesn't mean it's going to be easy. There's still unsavory characters in Gotham who want to make sure it doesn't change.
As for Dent's becoming Two-Face, I know now you have room to bring in Dent after Colson's death, but I wouldn't mind if he sat this series out. The arc of Dent in TDK is so iconic at this point, doing the rise and fall would just be repetitive. If you're going to go with Two-Face again, just dive head in with him being Two-Face akin to Joker. Or you could do a story where he tries to rehabilitate being Dent again if you want to bring in the struggle with the personality. I've always wanted to see a Two-Face scene play out like that Gollum scene in The Two Towers.