I don't think Dr. Strange, Silver Surfer, or Black Panther would do a MCP any favors. As great as the characters are, they don't really sell books anymore. If you have a headliner, it needs to be someone who people will show up for, then fill the rest of the book with people like Strange, Surfer, and Panther (as apposed to people like Type Face and the Winter Guard, who will draw about 3 people total).
It's hard to find people like that who aren't already headlining a book, but maybe Nova (Rider), Iron Fist, or Captain Britain. People who readers tend to like. Then fill the other stories with bigger to mediocre names with good stories. Have the plots important to the Marvel Universe. Have a price point that won't turn people away. $3 instead of $4 will do wonders for a book.
You know what I think I'd pitch if I were doing this? I'd have a Captain Britain feature bringing in aspects from his Moore days, Excalibur days, M-13 days, and recent Avenger days. Then I'd have side stories focusing on various New Warriors building toward the reunification of the surviving original New Warriors. Issue one might have Captain Britain in a story, then two stories featuring Justice and Firestar. The Next would continue the Captain Britain story and then aspects from the Justice and Firstar stories would roll into two new stories featuring Speedball and Namorita. The third issue would do the same but feature Night Thrasher (Donyell) and Rage. The fourth into Silhouette and Darkhawk (or Turbo or someone). Then come the fifth issue have only one feature that stars all of them together. By the end of the sixth or seventh issue have them stop the threat and decide to be a team again. All this time we have the Captain Britain main feature running, and the 3rd slott in the 5th and 6th issues (since there's only one NW plot now) would be filled for a 2 or 3 issue story featuring Iron Fist or a flashback tale of Ben Reilly.
Then just go with it so that the stories are staggering each other so if you're into Iron Fist plot from issues 5-7, you're also getting part of a Captain Britain plot against the Fury, then the start of the next Captain Britain plot where he helps Venom (Flash) with some problem he's having, as well as the end of the New Warriors plot and the start of whatever comes next. That way there's always something that keeps you coming back and maybe even buying back issues to see how one of the already running stories got to this point.
And I'd definately say no more than 3 stories per comic. Any more than that and there just isn't enough story to keep people these days.