Dude, you know they're not going to cancel this show after only a couple episodes. As I read earlier today, the pick-up of the show is a formality; Disney is just waiting to announce the full slate.
Introducing a major A2 character through the show strengthens the bond between the established MCU and its emerging TV sibling. And really, where's the risk here? People are already sold on A2. Those tickets are guaranteed. Putting in a character from S.H.I.E.L.D. can only work in the network's favor as it would instantly raise awareness for the show.
All that aside, a GOTG appearance--most likely as a cameo--could work too. However she gets in there, I'll be glad to see her. We need more female members on the team.