It could be fine, but it still is likely to take a big hit. Look at Spider-Man. Maybe the most popular superhero in the world, and Homecoming did pretty good with Marvel Studios after some substandard films. But even though it did well, it is hard to argue that he wasn't tarnished in some degree when his MCU movie is still massively underperforming characters like Black Panther and Captain Marvel. Spider-Man would normally be leading the MCU in box office results, not hanging around in the middle of the pack.