I don't think it's likely that Marvel Studios will take a break, because it's true, movie studios like making money. Standard practice is to take what's making money and just milk it and milk it relentlessly until all creatively is sucked dry and audiences are absolutely sick of it, lose interest, and start spending their money on something else. I'm just saying that's not necessarily the most creatively beneficial approach. If Marvel Studios can find a way to keep their cinematic universe fresh and vital post-Infinity War, of course I'll still be onboard.
But hey, let's not look to far ahead and wish away what's set to be the most exciting era ever for superhero cinema. The next 6 years are gonna be nerdvana, an age of movies that young me could only have dreamed about.